Barrett's esophagus is a condition where the tissue lining the esophagus (the tube that connects the throat to the stomach) is replaced by tissue that is similar to the lining of the intestine. This change in tissue is thought to be a response to chronic acid reflux and can increase the risk of developing esophageal cancer. Research in Barrett's esophagus focuses on understanding the underlying causes of the condition, as well as developing better methods for early detection and treatment to prevent the development of esophageal cancer. This research area also explores new treatment options, such as endoscopic therapies, to help manage Barrett's esophagus and reduce the risk of cancer progression.